KANPHOS_Str

Search Results (3 substrates found)

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Gene name
Organism
Protein name
Dcx
Mouse
Neuronal migration protein doublecortin
Substrate Information
Organism
Mouse (Mus musculus)
Uniprot ID
DCX_MOUSE
Accession #
O88809
Protein names
  • Neuronal migration protein doublecortin
  • Doublin
  • Lissencephalin-X
  • Lis-X
Gene names
  • Dcx
  • Dcn
Description
Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May participate along with PAFAH1B1/LIS-1 in a distinct overlapping signaling pathway that promotes neuronal migration (By similarity).
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Search Kinases of Dcx (Mouse)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
Mapt
Rat
Microtubule-associated protein tau
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
TAU_RAT
Accession #
P19332
Protein names
  • Microtubule-associated protein tau
  • Neurofibrillary tangle protein
  • Paired helical filament-tau
  • PHF-tau
Gene names
  • Mapt
  • Mtapt
  • Tau
Description
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Search Kinases of Mapt (Rat)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
MAPT
Human
Microtubule-associated protein tau
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
TAU_HUMAN
Accession #
P10636
Protein names
  • Microtubule-associated protein tau
  • Neurofibrillary tangle protein
  • Paired helical filament-tau
  • PHF-tau
Gene names
  • MAPT
  • MAPTL
  • MTBT1
  • TAU
Description
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Search Kinases of MAPT (Human)
Phosphorylation Site Information