KANPHOS_Str

Search Results (354 substrates found)

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Gene name
Organism
Protein name
Aatk
Mouse
Serine/threonine-protein kinase LMTK1
Substrate Information
Organism
Mouse (Mus musculus)
Uniprot ID
LMTK1_MOUSE
Accession #
Q80YE4
Protein names
  • Serine/threonine-protein kinase LMTK1
  • EC 2.7.11.1
  • Apoptosis-associated tyrosine kinase
  • AATYK
  • Brain apoptosis-associated tyrosine kinase
  • Lemur tyrosine kinase 1
Gene names
  • Aatk
  • Aatyk
  • Kiaa0641
  • Lmr1
  • Lmtk1
Description
May be involved in neuronal differentiation (By similarity).
Links

Search Kinases of Aatk (Mouse)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
Abce1
Rat
ATP-binding cassette, sub-family E
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
D3ZD23_RAT
Accession #
D3ZD23
Protein names
  • ATP-binding cassette, sub-family E
  • OABP, member 1
  • Protein Abce1
Gene names
  • Abce1
  • rCG_51692
Description
N/A
Links

Search Kinases of Abce1 (Rat)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
Abi2
Rat
Protein Abi2
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
F1LYA6_RAT
Accession #
F1LYA6
Protein names
  • Protein Abi2
Gene names
  • Abi2
Description
N/A
Links

Search Kinases of Abi2 (Rat)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
Acot9
Rat
Acyl-CoA thioesterase 9
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
Q5U2X8_RAT
Accession #
Q5U2X8
Protein names
  • Acyl-CoA thioesterase 9
  • Protein Acot9
  • Similar to acyl-CoA thioesterase, isoform CRA_b
Gene names
  • Acot9
  • LOC302640
  • rCG_36383
Description
N/A
Links

Search Kinases of Acot9 (Rat)
KEGG Pathways (0)
N/A
Gene Ontology Terms (0)
N/A
Phosphorylation Site Information
Actr3
Rat
Actin-related protein 3
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
ARP3_RAT
Accession #
Q4V7C7
Protein names
  • Actin-related protein 3
  • Actin-like protein 3
Gene names
  • Actr3
  • Arp3
Description
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis (By similarity).
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KEGG Pathways (0)
N/A
Phosphorylation Site Information
ADD2
Human
Beta-adducin
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
ADDB_HUMAN
Accession #
P35612
Protein names
  • Beta-adducin
  • Erythrocyte adducin subunit beta
Gene names
  • ADD2
  • ADDB
Description
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
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KEGG Pathways (0)
N/A
Phosphorylation Site Information
Agap2
Rat
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
AGAP2_RAT
Accession #
Q8CGU4
Protein names
  • Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
  • AGAP-2
  • Centaurin-gamma-1
  • Cnt-g1
  • Phosphatidylinositol 3-kinase enhancer
  • PIKE
Gene names
  • Agap2
  • Centg1
Description
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. Aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase.
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Phosphorylation Site Information
AGAP2
Human
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
AGAP2_HUMAN
Accession #
Q99490
Protein names
  • Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
  • AGAP-2
  • Centaurin-gamma-1
  • Cnt-g1
  • GTP-binding and GTPase-activating protein 2
  • GGAP2
  • Phosphatidylinositol 3-kinase enhancer
  • PIKE
Gene names
  • AGAP2
  • CENTG1
  • KIAA0167
Description
GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
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Search Kinases of AGAP2 (Human)
Phosphorylation Site Information
Ager
Rat
Advanced glycosylation end product-specific receptor
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
RAGE_RAT
Accession #
Q63495
Protein names
  • Advanced glycosylation end product-specific receptor
  • Receptor for advanced glycosylation end products
Gene names
  • Ager
  • Rage
Description
Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides (By similarity). Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
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Search Kinases of Ager (Rat)
KEGG Pathways (0)
N/A
Gene Ontology Terms (56)
Phosphorylation Site Information
Ahsg
Rat
Alpha-2-HS-glycoprotein
Aldoa
Rat
Fructose-bisphosphate aldolase A
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
ALDOA_RAT
Accession #
P05065
Protein names
  • Fructose-bisphosphate aldolase A
  • EC 4.1.2.13
  • Muscle-type aldolase
Gene names
  • Aldoa
Description
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
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Phosphorylation Site Information
Ampd3
Rat
AMP deaminase 3
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
F1M7Q5_RAT
Accession #
F1M7Q5
Protein names
  • AMP deaminase 3
  • Adenosine monophosphate deaminase 3, isoform CRA_c
Gene names
  • Ampd3
  • rCG_39800
Description
N/A
Links

Search Kinases of Ampd3 (Rat)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
AMPH
Human
Amphiphysin
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
AMPH_HUMAN
Accession #
P49418
Protein names
  • Amphiphysin
Gene names
  • AMPH
  • AMPH1
Description
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Links

Search Kinases of AMPH (Human)
Phosphorylation Site Information
Amph
Rat
Amphiphysin
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
AMPH_RAT
Accession #
O08838
Protein names
  • Amphiphysin
Gene names
  • Amph
  • Amph1
Description
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity).
Links

Search Kinases of Amph (Rat)
Phosphorylation Site Information
Ank2
Rat
Protein Ank2
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
F1LM42_RAT
Accession #
F1LM42
Protein names
  • Protein Ank2
Gene names
  • Ank2
Description
N/A
Links

Search Kinases of Ank2 (Rat)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
Ank3
Rat
Ankyrin-3
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
ANK3_RAT
Accession #
O70511
Protein names
  • Ankyrin-3
  • ANK-3
  • Ankyrin-G
Gene names
  • Ank3
Description
Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity).
Links

Search Kinases of Ank3 (Rat)
KEGG Pathways (1)
Phosphorylation Site Information
Ankrd34a
Rat
Ankyrin repeat domain-containing protein 34A
Substrate Information
Organism
Rat (Rattus norvegicus)
Uniprot ID
AN34A_RAT
Accession #
Q5BJT1
Protein names
  • Ankyrin repeat domain-containing protein 34A
Gene names
  • Ankrd34a
Description
N/A
Links

Search Kinases of Ankrd34a (Rat)
KEGG Pathways (0)
N/A
Gene Ontology Terms (1)
Phosphorylation Site Information
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