Search Results (1041 substrates found)
Gene name
Organism
Protein name
A8K3D9
Human
cDNA FLJ76018, highly similar to Homo sapiens cell division cycle 25A
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
A8K3D9_HUMAN
- Accession #
- A8K3D9
- Protein names
-
- cDNA FLJ76018, highly similar to Homo sapiens cell division cycle 25A
- CDC25A, transcript variant 1, mRNA
- Gene names
-
- A8K3D9
- Description
-
N/A
- Links
-
Search Kinases of A8K3D9 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (3)
Phosphorylation Site Information
A8KM8
Human
cDNA FLJ78057, highly similar to Homo sapiens differential display and activated by p53
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
A8K0M8_HUMAN
- Accession #
- A8K0M8
- Protein names
-
- cDNA FLJ78057, highly similar to Homo sapiens differential display and activated by p53
- DDA3,mRNA
- Gene names
-
- A8KM8
- Description
-
N/A
- Links
-
Search Kinases of A8KM8 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (0)
N/A
Phosphorylation Site Information
A8KP2
Human
cDNA FLJ76209, highly similar to Homo sapiens inorganic pyrophosphatase 2
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
A8K0P2_HUMAN
- Accession #
- A8K0P2
- Protein names
-
- cDNA FLJ76209, highly similar to Homo sapiens inorganic pyrophosphatase 2
- PPA2, transcript variant 2, mRNA
- Gene names
-
- A8KP2
- Description
-
N/A
- Links
-
Search Kinases of A8KP2 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (4)
Phosphorylation Site Information
A8KX7
Human
cDNA FLJ75103, highly similar to Homo sapiens protein tyrosine phosphatase domain containing 1
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
A8K0X7_HUMAN
- Accession #
- A8K0X7
- Protein names
-
- cDNA FLJ75103, highly similar to Homo sapiens protein tyrosine phosphatase domain containing 1
- PTPDC1, transcript variant 1, mRNA
- Gene names
-
- A8KX7
- Description
-
N/A
- Links
-
Search Kinases of A8KX7 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (2)
Phosphorylation Site Information
ABCA1
Human
ATP-binding cassette sub-family A member 1
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
ABCA1_HUMAN
- Accession #
-
O95477
- Protein names
-
- ATP-binding cassette sub-family A member 1
- ATP-binding cassette transporter 1
- ABC-1
- ATP-binding cassette 1
- Cholesterol efflux regulatory protein
- Gene names
-
- ABCA1
- ABC1
- CERP
- Description
-
cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.
- Links
-
Search Kinases of ABCA1 (Human)
KEGG Pathways (2)
Gene Ontology Terms (56)
- ATP binding
- ATPase activity
- ATPase binding
- G-protein coupled receptor signaling pathway
- Golgi apparatus
- anion transmembrane transporter activity
- apolipoprotein A-I binding
- apolipoprotein A-I receptor activity
- apolipoprotein A-I-mediated signaling pathway
- apolipoprotein binding
- cell surface
- cellular lipid metabolic process
- cellular response to cholesterol
- cellular response to lipopolysaccharide
- cellular response to retinoic acid
- cholesterol binding
- cholesterol efflux
- cholesterol homeostasis
- cholesterol metabolic process
- cholesterol transporter activity
- endocytic vesicle
- endosomal transport
- high-density lipoprotein particle assembly
- integral component of plasma membrane
- interleukin-1 beta secretion
- intracellular cholesterol transport
- lipoprotein metabolic process
- lysosome organization
- membrane raft
- negative regulation of cholesterol storage
- negative regulation of macrophage derived foam cell differentiation
- peptide secretion
- perinuclear region of cytoplasm
- phagocytic vesicle
- phagocytosis, engulfment
- phospholipid binding
- phospholipid efflux
- phospholipid homeostasis
- phospholipid translocation
- phospholipid transporter activity
- plasma membrane
- platelet dense granule organization
- positive regulation of cAMP biosynthetic process
- positive regulation of cholesterol efflux
- protein binding
- protein lipidation
- receptor binding
- regulation of Cdc42 protein signal transduction
- response to drug
- response to laminar fluid shear stress
- response to low-density lipoprotein particle
- response to nutrient
- reverse cholesterol transport
- small GTPase binding
- small molecule metabolic process
- syntaxin binding
Phosphorylation Site Information
ABCB1
Human
Multidrug resistance protein 1
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
MDR1_HUMAN
- Accession #
-
P08183
- Protein names
-
- Multidrug resistance protein 1
- EC 3.6.3.44
- ATP-binding cassette sub-family B member 1
- P-glycoprotein 1
- CD antigen CD243
- Gene names
-
- ABCB1
- MDR1
- PGY1
- Description
-
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
- Links
-
Search Kinases of ABCB1 (Human)
KEGG Pathways (3)
Gene Ontology Terms (17)
- ATP binding
- ATPase activity, coupled to transmembrane movement of substances
- G2/M transition of mitotic cell cycle
- cell surface
- drug transmembrane transport
- extracellular vesicular exosome
- integral component of membrane
- membrane
- plasma membrane
- protein binding
- response to drug
- small molecule metabolic process
- stem cell proliferation
- transmembrane transport
- transport
- transporter activity
- xenobiotic-transporting ATPase activity
Phosphorylation Site Information
Abcc9
Mouse
ATP-binding cassette sub-family C member 9
Substrate Information
- Organism
- Mouse (Mus musculus)
- Uniprot ID
-
ABCC9_MOUSE
- Accession #
-
P70170
- Protein names
-
- ATP-binding cassette sub-family C member 9
- Sulfonylurea receptor 2
- Gene names
-
- Abcc9
- Sur2
- Description
-
Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
- Links
-
Search Kinases of Abcc9 (Mouse)
KEGG Pathways (1)
Gene Ontology Terms (9)
Phosphorylation Site Information
ABTB1
Human
Ankyrin repeat and BTB/POZ domain-containing protein 1
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
ABTB1_HUMAN
- Accession #
-
Q969K4
- Protein names
-
- Ankyrin repeat and BTB/POZ domain-containing protein 1
- Elongation factor 1A-binding protein
- Gene names
-
- ABTB1
- BPOZ
- PP2259
- Description
-
May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.
- Links
-
Search Kinases of ABTB1 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (4)
Phosphorylation Site Information
Acaca
Rat
Acetyl-CoA carboxylase 1
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACACA_RAT
- Accession #
-
P11497
- Protein names
-
- Acetyl-CoA carboxylase 1
- ACC1
- EC 6.4.1.2
- ACC-alpha [Includes: Biotin carboxylase
- EC 6.3.4.14]
- Gene names
-
- Acaca
- Acac
- Description
-
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
- Links
-
Search Kinases of Acaca (Rat)
KEGG Pathways (7)
Gene Ontology Terms (13)
- ATP binding
- acetyl-CoA carboxylase activity
- acetyl-CoA metabolic process
- biotin binding
- biotin carboxylase activity
- cytosol
- fatty acid biosynthetic process
- kinase binding
- malonyl-CoA biosynthetic process
- metal ion binding
- protein homotetramerization
- response to drug
- response to organic cyclic compound
Phosphorylation Site Information
Acta1
Rat
Actin, alpha skeletal muscle
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACTS_RAT
- Accession #
-
P68136
- Protein names
-
- Actin, alpha skeletal muscle
- Alpha-actin-1
- Gene names
-
- Acta1
- Acta
- Description
-
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
- Links
-
Search Kinases of Acta1 (Rat)
KEGG Pathways (0)
N/A
Gene Ontology Terms (13)
- ATP binding
- actin filament
- cell growth
- extracellular vesicular exosome
- response to extracellular stimulus
- response to lithium ion
- response to mechanical stimulus
- response to steroid hormone
- skeletal muscle fiber adaptation
- skeletal muscle fiber development
- skeletal muscle thin filament assembly
- stress fiber
- striated muscle thin filament
Phosphorylation Site Information
Actb
Rat
Actin, cytoplasmic 1
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACTB_RAT
- Accession #
-
P60711
- Protein names
-
- Actin, cytoplasmic 1
- Beta-actin [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
- Gene names
-
- Actb
- Description
-
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
- Links
-
Search Kinases of Actb (Rat)
KEGG Pathways (20)
- Adherens junction
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Bacterial invasion of epithelial cells
- Dilated cardiomyopathy
- Focal adhesion
- Gastric acid secretion
- Hippo signaling pathway
- Hypertrophic cardiomyopathy (HCM)
- Influenza A
- Leukocyte transendothelial migration
- Oxytocin signaling pathway
- Phagosome
- Platelet activation
- Proteoglycans in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- Salmonella infection
- Thyroid hormone signaling pathway
- Tight junction
- Viral myocarditis
Gene Ontology Terms (12)
Phosphorylation Site Information
Actg1
Rat
Actin, cytoplasmic 2
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACTG_RAT
- Accession #
-
P63259
- Protein names
-
- Actin, cytoplasmic 2
- Gamma-actin [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
- Gene names
-
- Actg1
- Actg
- Description
-
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
- Links
-
Search Kinases of Actg1 (Rat)
KEGG Pathways (19)
- Adherens junction
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
- Bacterial invasion of epithelial cells
- Dilated cardiomyopathy
- Focal adhesion
- Hippo signaling pathway
- Hypertrophic cardiomyopathy (HCM)
- Influenza A
- Leukocyte transendothelial migration
- Oxytocin signaling pathway
- Phagosome
- Platelet activation
- Proteoglycans in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- Salmonella infection
- Thyroid hormone signaling pathway
- Tight junction
- Viral myocarditis
Gene Ontology Terms (4)
Phosphorylation Site Information
Actg1
Mouse
Gamma actin-like protein
Substrate Information
- Organism
- Mouse (Mus musculus)
- Uniprot ID
-
Q9QZ83_MOUSE
- Accession #
- Q9QZ83
- Protein names
-
- Gamma actin-like protein
- Gene names
-
- Actg1
- Actl
- Description
-
N/A
- Links
-
Search Kinases of Actg1 (Mouse)
KEGG Pathways (0)
N/A
Gene Ontology Terms (7)
Phosphorylation Site Information
Actg2
Rat
Actin, gamma-enteric smooth muscle
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACTH_RAT
- Accession #
-
P63269
- Protein names
-
- Actin, gamma-enteric smooth muscle
- Alpha-actin-3
- Gamma-2-actin
- Smooth muscle gamma-actin
- Gene names
-
- Actg2
- Acta3
- Actsg
- Description
-
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
- Links
-
Search Kinases of Actg2 (Rat)
KEGG Pathways (1)
Gene Ontology Terms (4)
Phosphorylation Site Information
Actn1
Rat
Alpha-actinin-1
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACTN1_RAT
- Accession #
-
Q9Z1P2
- Protein names
-
- Alpha-actinin-1
- Alpha-actinin cytoskeletal isoform
- F-actin cross-linking protein
- Non-muscle alpha-actinin-1
- Gene names
-
- Actn1
- Description
-
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).
- Links
-
Search Kinases of Actn1 (Rat)
KEGG Pathways (9)
Gene Ontology Terms (19)
- Z disc
- actin crosslink formation
- actin filament bundle assembly
- calcium ion binding
- cytoplasm
- cytoskeleton
- cytosol
- dendritic spine
- double-stranded RNA binding
- extracellular vesicular exosome
- fascia adherens
- focal adhesion
- focal adhesion assembly
- negative regulation of cellular component movement
- nucleus
- plasma membrane
- protein binding
- protein domain specific binding
- ruffle
Phosphorylation Site Information
Actn4
Rat
Alpha-actinin-4
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ACTN4_RAT
- Accession #
-
Q9QXQ0
- Protein names
-
- Alpha-actinin-4
- F-actin cross-linking protein
- Non-muscle alpha-actinin 4
- Gene names
-
- Actn4
- Description
-
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity).
- Links
-
Search Kinases of Actn4 (Rat)
KEGG Pathways (9)
Gene Ontology Terms (26)
- Z disc
- actin filament bundle assembly
- calcium ion binding
- cell-cell junction
- cortical cytoskeleton
- cytoplasm
- cytosol
- extracellular vesicular exosome
- negative regulation of cellular component movement
- neuron projection
- nucleoside binding
- nucleus
- perinuclear region of cytoplasm
- positive regulation of cellular component movement
- positive regulation of pinocytosis
- protein N-terminus binding
- protein binding
- protein complex
- protein complex binding
- protein transport
- pseudopodium
- regulation of apoptotic process
- response to hypoxia
- ribonucleoprotein complex
- stress fiber
- tight junction assembly
Phosphorylation Site Information
Add1
Rat
Alpha-adducin
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
ADDA_RAT
- Accession #
-
Q63028
- Protein names
-
- Alpha-adducin
- Erythrocyte adducin subunit alpha
- Gene names
-
- Add1
- Description
-
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
- Links
-
Search Kinases of Add1 (Rat)
KEGG Pathways (0)
N/A
Gene Ontology Terms (27)
- F-actin capping protein complex
- T cell receptor binding
- actin filament bundle assembly
- barbed-end actin filament capping
- cell morphogenesis
- cell volume homeostasis
- cellular response to retinoic acid
- cytoskeleton organization
- dendrite
- dendritic spine
- erythrocyte differentiation
- hemoglobin metabolic process
- homeostasis of number of cells within a tissue
- in utero embryonic development
- ion transport
- multicellular organism growth
- negative regulation of actin filament polymerization
- nucleus
- perinuclear region of cytoplasm
- plasma membrane
- positive regulation of angiogenesis
- positive regulation of endocytosis
- positive regulation of protein binding
- postsynaptic density
- protein binding
- structural molecule activity
- synapse
Phosphorylation Site Information
ADD1
Human
Alpha-adducin
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
ADDA_HUMAN
- Accession #
-
P35611
- Protein names
-
- Alpha-adducin
- Erythrocyte adducin subunit alpha
- Gene names
-
- ADD1
- ADDA
- Description
-
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
- Links
-
Search Kinases of ADD1 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (35)
- F-actin capping protein complex
- actin binding
- actin cytoskeleton organization
- actin filament binding
- actin filament bundle assembly
- activation of signaling protein activity involved in unfolded protein response
- apoptotic process
- barbed-end actin filament capping
- cell morphogenesis
- cell volume homeostasis
- cellular component disassembly involved in execution phase of apoptosis
- cellular protein metabolic process
- cellular response to retinoic acid
- cytosol
- dendritic spine
- endoplasmic reticulum unfolded protein response
- erythrocyte differentiation
- hemoglobin metabolic process
- homeostasis of number of cells within a tissue
- in utero embryonic development
- intermediate filament cytoskeleton
- multicellular organism growth
- nucleus
- perinuclear region of cytoplasm
- plasma membrane
- poly(A) RNA binding
- positive regulation of angiogenesis
- positive regulation of endocytosis
- positive regulation of protein binding
- postsynaptic density
- protein heterodimerization activity
- protein homodimerization activity
- spectrin binding
- structural molecule activity
- transcription factor binding
Phosphorylation Site Information
ADD2
Human
Beta-adducin
Substrate Information
- Organism
- Human (Homo sapiens)
- Uniprot ID
-
ADDB_HUMAN
- Accession #
-
P35612
- Protein names
-
- Beta-adducin
- Erythrocyte adducin subunit beta
- Gene names
-
- ADD2
- ADDB
- Description
-
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
- Links
-
Search Kinases of ADD2 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (15)
- F-actin capping protein complex
- actin binding
- actin cytoskeleton organization
- actin filament binding
- actin filament bundle assembly
- barbed-end actin filament capping
- cytoplasmic membrane-bounded vesicle
- hemopoiesis
- plasma membrane
- positive regulation of protein binding
- protein complex assembly
- protein heterodimerization activity
- protein homodimerization activity
- spectrin binding
- structural molecule activity
Phosphorylation Site Information
Add2
Rat
Beta-adducin
Substrate Information
- Organism
- Rat (Rattus norvegicus)
- Uniprot ID
-
F8WFS9_RAT
- Accession #
- F8WFS9
- Protein names
-
- Beta-adducin
- Gene names
-
- Add2
- Description
-
N/A
- Links
-
Search Kinases of Add2 (Rat)
KEGG Pathways (0)
N/A
Gene Ontology Terms (9)
Phosphorylation Site Information