KANPHOS_Str

Search Results (15 substrates found)

Displaying 1 - 15 of 15 Items
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Gene name
Organism
Protein name
ARL6IP4
Human
ADP-ribosylation factor-like protein 6-interacting protein 4
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
AR6P4_HUMAN
Accession #
Q66PJ3
Protein names
  • ADP-ribosylation factor-like protein 6-interacting protein 4
  • ARL-6-interacting protein 4
  • Aip-4
  • HSP-975
  • HSVI-binding protein
  • SR-15
  • SRp25
  • SR-25
  • Splicing factor SRrp37
Gene names
  • ARL6IP4
Description
Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site. In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA. {ECO:0000269|PubMed:19582790}.
Links

Search Kinases of ARL6IP4 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
C1orf174
Human
UPF0688 protein C1orf174
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
CA174_HUMAN
Accession #
Q8IYL3
Protein names
  • UPF0688 protein C1orf174
Gene names
  • C1orf174
Description
N/A
Links

Search Kinases of C1orf174 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (1)
Phosphorylation Site Information
CWC15
Human
Spliceosome-associated protein CWC15 homolog
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
CWC15_HUMAN
Accession #
Q9P013
Protein names
  • Spliceosome-associated protein CWC15 homolog
Gene names
  • CWC15
  • C11orf5
  • AD-002
  • HSPC148
Description
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:28076346). Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. {ECO:0000269|PubMed:20176811, ECO:0000269|PubMed:28076346, ECO:0000269|PubMed:28502770}.
Links

Search Kinases of CWC15 (Human)
KEGG Pathways (1)
Phosphorylation Site Information
DNAJC16
Human
DnaJ homolog subfamily C member 16
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
DJC16_HUMAN
Accession #
Q9Y2G8
Protein names
  • DnaJ homolog subfamily C member 16
Gene names
  • DNAJC16
  • KIAA0962
Description
N/A
Links

Search Kinases of DNAJC16 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (1)
Phosphorylation Site Information
EFHD2
Human
EF-hand domain-containing protein D2
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
EFHD2_HUMAN
Accession #
Q96C19
Protein names
  • EF-hand domain-containing protein D2
  • Swiprosin-1
Gene names
  • EFHD2
  • SWS1
Description
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. {ECO:0000250}.
Links

Search Kinases of EFHD2 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
FAH
Human
Fumarylacetoacetase
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
FAAA_HUMAN
Accession #
P16930
Protein names
  • Fumarylacetoacetase
  • FAA
  • EC 3.7.1.2
  • Beta-diketonase
  • Fumarylacetoacetate hydrolase
Gene names
  • FAH
Description
N/A
Links

Search Kinases of FAH (Human)
Phosphorylation Site Information
GTF2F1
Human
General transcription factor IIF subunit 1
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
T2FA_HUMAN
Accession #
P35269
Protein names
  • General transcription factor IIF subunit 1
  • General transcription factor IIF 74 kDa subunit
  • Transcription initiation factor IIF subunit alpha
  • TFIIF-alpha
  • Transcription initiation factor RAP74
Gene names
  • GTF2F1
  • RAP74
Description
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. {ECO:0000269|PubMed:10428810}.
Links

Search Kinases of GTF2F1 (Human)
Phosphorylation Site Information
JHY
Human
Jhy protein homolog
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
JHY_HUMAN
Accession #
Q6NUN7
Protein names
  • Jhy protein homolog
Gene names
  • JHY
  • C11orf63
Description
Required for the normal development of cilia in brain ependymal cells lining the ventricular surfaces. {ECO:0000250|UniProtKB:E9Q793}.
Links

Search Kinases of JHY (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
LMOD1
Human
Leiomodin-1
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
LMOD1_HUMAN
Accession #
P29536
Protein names
  • Leiomodin-1
  • 64 kDa autoantigen 1D
  • 64 kDa autoantigen 1D3
  • 64 kDa autoantigen D1
  • Leiomodin, muscle form
  • Smooth muscle leiomodin
  • SM-Lmod
  • Thyroid-associated ophthalmopathy autoantigen
Gene names
  • LMOD1
Description
Mediates nucleation of actin filaments. {ECO:0000269|PubMed:26370058}.
Links

Search Kinases of LMOD1 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
METTL1
Human
tRNA
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
TRMB_HUMAN
Accession #
Q9UBP6
Protein names
  • tRNA
  • guanine-N(7
  • EC 2.1.1.33
  • Methyltransferase-like protein 1
  • mRNA (guanine-N(7
  • EC 2.1.1.-
  • miRNA (guanine-N(7
Gene names
  • METTL1
  • C12orf1
Description
Methyltransferase that mediates the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) (PubMed:12403464, PubMed:31031084, PubMed:31031083). Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (PubMed:12403464, PubMed:31031084). Also acts as a methyltransferase for a subset of internal N(7)-methylguanine in mRNAs (PubMed:31031084). Internal N(7)-methylguanine methylation of mRNAs regulates translation (PubMed:31031084). Also methylates a specific subset of miRNAs, such as let-7 (PubMed:31031083). N(7)-methylguanine methylation of let-7 miRNA promotes let-7 miRNA processing by disrupting an inhibitory secondary structure within the primary miRNA transcript (pri-miRNA) (PubMed:31031083). Acts as a regulator of embryonic stem cell self-renewal and differentiation (By similarity). {ECO:0000255|HAMAP-Rule:MF_03055, ECO:0000269|PubMed:12403464, ECO:0000269|PubMed:31031083, ECO:0000269|PubMed:31031084}.
Links

Search Kinases of METTL1 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
PIGS
Human
GPI transamidase component PIG-S
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
PIGS_HUMAN
Accession #
Q96S52
Protein names
  • GPI transamidase component PIG-S
  • Phosphatidylinositol-glycan biosynthesis class S protein
Gene names
  • PIGS
  • UNQ1873/PRO4316
Description
Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates. {ECO:0000269|PubMed:11483512, ECO:0000269|PubMed:30269814}.
Links

Search Kinases of PIGS (Human)
Phosphorylation Site Information
PSME3IP1
Human
PSME3-interacting protein
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
PIP30_HUMAN
Accession #
Q9GZU8
Protein names
  • PSME3-interacting protein
  • NEFA-interacting nuclear protein NIP30
  • PA28G-interacting protein
Gene names
  • PSME3IP1
  • C16orf94
  • FAM192A
  • NIP30
  • PIP30
  • CDA018
  • CDA10
Description
Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus. {ECO:0000269|PubMed:29934401}.
Links

Search Kinases of PSME3IP1 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
RNF13
Human
E3 ubiquitin-protein ligase RNF13
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
RNF13_HUMAN
Accession #
O43567
Protein names
  • E3 ubiquitin-protein ligase RNF13
  • EC 2.3.2.27
  • RING finger protein 13
  • RING-type E3 ubiquitin transferase RNF13
Gene names
  • RNF13
  • RZF
Description
E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA (PubMed:23378536, PubMed:30595371). {ECO:0000269|PubMed:18794910, ECO:0000269|PubMed:23378536, ECO:0000269|PubMed:30595371}.
Links

Search Kinases of RNF13 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information
RPAP3
Human
RNA polymerase II-associated protein 3
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
RPAP3_HUMAN
Accession #
Q9H6T3
Protein names
  • RNA polymerase II-associated protein 3
Gene names
  • RPAP3
Description
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. {ECO:0000269|PubMed:17643375}.
Links

Search Kinases of RPAP3 (Human)
KEGG Pathways (0)
N/A
Gene Ontology Terms (2)
Phosphorylation Site Information
RTN2
Human
Reticulon
Substrate Information
Organism
Human (Homo sapiens)
Uniprot ID
Q6GMT0_HUMAN
Accession #
Q6GMT0
Protein names
  • Reticulon
Gene names
  • RTN2
Description
N/A
Links

Search Kinases of RTN2 (Human)
KEGG Pathways (0)
N/A
Phosphorylation Site Information